Chaste Commit::ca8ccdedf819b6e02855bc0e8e6f50bdecbc5208
AbstractSimplePhaseBasedCellCycleModel Class Reference

#include <AbstractSimplePhaseBasedCellCycleModel.hpp>

+ Inheritance diagram for AbstractSimplePhaseBasedCellCycleModel:
+ Collaboration diagram for AbstractSimplePhaseBasedCellCycleModel:

Public Member Functions

 AbstractSimplePhaseBasedCellCycleModel ()
 
virtual ~AbstractSimplePhaseBasedCellCycleModel ()
 
virtual void ResetForDivision ()
 
virtual void UpdateCellCyclePhase ()
 
void InitialiseDaughterCell ()
 
virtual void Initialise ()
 
virtual void OutputCellCycleModelParameters (out_stream &rParamsFile)
 
- Public Member Functions inherited from AbstractPhaseBasedCellCycleModel
 AbstractPhaseBasedCellCycleModel ()
 
virtual ~AbstractPhaseBasedCellCycleModel ()
 
virtual bool ReadyToDivide ()
 
CellCyclePhase GetCurrentCellCyclePhase () const
 
virtual double GetG1Duration () const
 
double GetStemCellG1Duration () const
 
double GetTransitCellG1Duration () const
 
double GetSG2MDuration () const
 
virtual double GetSDuration () const
 
virtual double GetG2Duration () const
 
virtual double GetMDuration () const
 
virtual void SetStemCellG1Duration (double stemCellG1Duration)
 
virtual void SetTransitCellG1Duration (double transitCellG1Duration)
 
void SetSDuration (double sDuration)
 
void SetG2Duration (double g2Duration)
 
void SetMDuration (double mDuration)
 
virtual double GetAverageTransitCellCycleTime ()
 
virtual double GetAverageStemCellCycleTime ()
 
double GetMinimumGapDuration () const
 
void SetMinimumGapDuration (double minimumGapDuration)
 
- Public Member Functions inherited from AbstractCellCycleModel
 AbstractCellCycleModel ()
 
virtual ~AbstractCellCycleModel ()
 
void SetCell (CellPtr pCell)
 
CellPtr GetCell ()
 
virtual void SetBirthTime (double birthTime)
 
void SetDimension (unsigned dimension)
 
unsigned GetDimension () const
 
double GetBirthTime () const
 
double GetAge ()
 
virtual AbstractCellCycleModelCreateCellCycleModel ()=0
 
virtual bool CanCellTerminallyDifferentiate ()
 
void OutputCellCycleModelInfo (out_stream &rParamsFile)
 
- Public Member Functions inherited from Identifiable
virtual ~Identifiable ()
 
std::string GetIdentifier () const
 

Protected Member Functions

virtual void SetG1Duration ()
 
 AbstractSimplePhaseBasedCellCycleModel (const AbstractSimplePhaseBasedCellCycleModel &rModel)
 
- Protected Member Functions inherited from AbstractPhaseBasedCellCycleModel
 AbstractPhaseBasedCellCycleModel (const AbstractPhaseBasedCellCycleModel &rModel)
 
- Protected Member Functions inherited from AbstractCellCycleModel
 AbstractCellCycleModel (const AbstractCellCycleModel &rModel)
 

Private Member Functions

template<class Archive >
void serialize (Archive &archive, const unsigned int version)
 

Friends

class boost::serialization::access
 

Additional Inherited Members

- Protected Attributes inherited from AbstractPhaseBasedCellCycleModel
CellCyclePhase mCurrentCellCyclePhase
 
double mG1Duration
 
double mMinimumGapDuration
 
double mStemCellG1Duration
 
double mTransitCellG1Duration
 
double mSDuration
 
double mG2Duration
 
double mMDuration
 
- Protected Attributes inherited from AbstractCellCycleModel
CellPtr mpCell
 
double mBirthTime
 
bool mReadyToDivide
 
unsigned mDimension
 

Detailed Description

This class contains all the functionality shared by 'simple' cell-cycle models, where the duration of each cell cycle phase is determined when the cell-cycle model is created. Note that whether or not the cell should actually divide may still depend on further conditions in subclasses; for example, the cell may only divide if the local concentration of a signalling molecule is sufficiently high/

This class of cell-cycle models is distinct from 'ODE-based' cell-cycle models, where the duration of one or more cell cycle phases are evaluated 'on the fly' as the cell ages, according to a system of ordinary differential equations (ODEs) governing (for example) the concentrations of key intracellular proteins.

Definition at line 57 of file AbstractSimplePhaseBasedCellCycleModel.hpp.

Constructor & Destructor Documentation

◆ AbstractSimplePhaseBasedCellCycleModel() [1/2]

AbstractSimplePhaseBasedCellCycleModel::AbstractSimplePhaseBasedCellCycleModel ( const AbstractSimplePhaseBasedCellCycleModel rModel)
protected

Protected copy-constructor for use by CreateCellCycleModel. The only way for external code to create a copy of a cell cycle model is by calling that method, to ensure that a model of the correct subclass is created. This copy-constructor helps subclasses to ensure that all member variables are correctly copied when this happens.

This method is called by child classes to set member variables for a daughter cell upon cell division. Note that the parent cell cycle model will have had ResetForDivision() called just before CreateCellCycleModel() is called, so performing an exact copy of the parent is suitable behaviour. Any daughter-cell-specific initialisation can be done in InitialiseDaughterCell().

Parameters
rModelthe cell cycle model to copy.

Definition at line 49 of file AbstractSimplePhaseBasedCellCycleModel.cpp.

◆ AbstractSimplePhaseBasedCellCycleModel() [2/2]

AbstractSimplePhaseBasedCellCycleModel::AbstractSimplePhaseBasedCellCycleModel ( )

Default constructor - creates an AbstractSimplePhaseBasedCellCycleModel.

Definition at line 41 of file AbstractSimplePhaseBasedCellCycleModel.cpp.

◆ ~AbstractSimplePhaseBasedCellCycleModel()

AbstractSimplePhaseBasedCellCycleModel::~AbstractSimplePhaseBasedCellCycleModel ( )
virtual

Destructor.

Definition at line 45 of file AbstractSimplePhaseBasedCellCycleModel.cpp.

Member Function Documentation

◆ Initialise()

void AbstractSimplePhaseBasedCellCycleModel::Initialise ( )
virtual

◆ InitialiseDaughterCell()

void AbstractSimplePhaseBasedCellCycleModel::InitialiseDaughterCell ( )
virtual

Set the new cell's G1 duration once it has been created after division. The duration will be based on cell type.

Reimplemented from AbstractCellCycleModel.

Reimplemented in StochasticOxygenBasedCellCycleModel, and SimpleWntCellCycleModel.

Definition at line 71 of file AbstractSimplePhaseBasedCellCycleModel.cpp.

References AbstractCellCycleModel::InitialiseDaughterCell(), and SetG1Duration().

Referenced by AbstractSimpleGenerationalCellCycleModel::InitialiseDaughterCell(), and SimpleWntCellCycleModel::InitialiseDaughterCell().

◆ OutputCellCycleModelParameters()

◆ ResetForDivision()

◆ serialize()

template<class Archive >
void AbstractSimplePhaseBasedCellCycleModel::serialize ( Archive &  archive,
const unsigned int  version 
)
inlineprivate

Archive the cell-cycle model.

Parameters
archivethe archive
versionthe current version of this class

Definition at line 70 of file AbstractSimplePhaseBasedCellCycleModel.hpp.

◆ SetG1Duration()

void AbstractSimplePhaseBasedCellCycleModel::SetG1Duration ( )
protectedvirtual

◆ UpdateCellCyclePhase()

Friends And Related Symbol Documentation

◆ boost::serialization::access

friend class boost::serialization::access
friend

Needed for serialization.

Definition at line 62 of file AbstractSimplePhaseBasedCellCycleModel.hpp.


The documentation for this class was generated from the following files: